Tailored Intervention to Improve Medication Adherence in Patients With Hypertension

Not Applicable

Completed

• Conditions: Hypertension
• Interventions: Behavioral: Usual care; Behavioral: Complex tailored intervention

• Registration Number: NCT01742923
• Lead Sponsor: Odense University Hospital

Brief Summary

Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group. The purpose of this study is to investigate whether a complex tailored intervention in a hospital setting will lead to increased medication adherence and fewer cardiovascular events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-12
• Study First Submitted: 2012-12-04
• Study First Submitted QC: 2012-12-04
• Study First Posted: 2012-12-06
• Primary Completion: 2014-08
• Study Completion: 2014-09
• Status Verified: 2015-11
• Last Update Submitted: 2015-11-17
• Last Update Posted: 2015-11-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 532

Inclusion Criteria

Age: 18 years or older

• Patients receiving ambulatory treatment for hypertension in a hospital setting
• The patient or a carer usually dispenses the patient's medications
• Patient lives in the Southern Region of Denmark
• Written consent

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Exclusion Criteria

• Lives in a care home or institution
• Receive dose dispensed medicine from a pharmacy
• Medicine is dispensed by a nurse in the patient's home
• Correctional mental health patients

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Usual care	Usual care	Usual care
Complex tailored intervention	Complex tailored intervention	The interventions consists of 3 elements: 1. Medication review with recommendations focused on antihypertensives and statins and adherence to guidelines and patient´s adherence to medications 2. Consultation with a pharmacist using motivational interviewing techniques 3. Follow-up telephone calls one month and six months after inclusion

Primary Outcome Measures

Name	Time	Method
Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins	One year from inclusion

Secondary Outcome Measures

Name	Time	Method
Non-persistence with antihypertensives and statins measured by percent of patients that are not supplied with medications for more than three continuous months	One year from inclusion
Reduction in systolic and diastolic blood pressure	One year from inclusion
Composite endpoint (stroke, myocardial infarction or cardiovascular death)	One year from inclusion

Trial Locations

Locations (1)

Odense University Hospital; 🇩🇰 Odense C, Denmark