Pharmacist Intervention Programme in Secondary Care to Improve Medication Adherence in Patients With Hypertension
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Odense University Hospital
- Enrollment
- 532
- Locations
- 2
- Primary Endpoint
- Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins
Study Overview
Brief Summary
Patients with hypertension have an increased risk of stroke and myocardial infarction. However, poor adherence to treatment with antihypertensives and lipid-lowering agents occurs frequently within this patient group. The purpose of this study is to investigate whether a complex tailored intervention in a hospital setting will lead to increased medication adherence and fewer cardiovascular events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Age: 18 years or older
- •Patients receiving ambulatory treatment for hypertension in a hospital setting
- •The patient or a carer usually dispenses the patient's medications
- •Patient lives in the Southern Region of Denmark
- •Written consent
Exclusion Criteria
- •Lives in a care home or institution
- •Receive dose dispensed medicine from a pharmacy
- •Medicine is dispensed by a nurse in the patient's home
- •Correctional mental health patients
Outcomes
Primary Outcomes
Percent of patients that are at least 80% adherent (Medication possession rate > 0.8) to antihypertensives and statins
Time Frame: One year from inclusion
Secondary Outcomes
- Non-persistence with antihypertensives and statins measured by percent of patients that are not supplied with medications for more than three continuous months(One year from inclusion)
- Reduction in systolic and diastolic blood pressure(One year from inclusion)
- Composite endpoint (stroke, myocardial infarction or cardiovascular death)(One year from inclusion)
Investigators
Ulla Hedegaard
PhD student, MSc (pharm), Odense University Hospital
Odense University Hospital