Pharmacist Intervention Programme to Improve Medication Adherence in Stroke Patients
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Stroke
- Sponsor
- Odense University Hospital
- Enrollment
- 211
- Locations
- 1
- Primary Endpoint
- Medication Adherence to antiplatelets, anticoagulants and statins measured by proportion of days covered (PDC).
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group. The purpose of this study is to evaluate whether a complex tailored pharmacist intervention will lead to increased adherence to secondary stroke prevention medications and less new stroke events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.
Investigators
Ulla Hedegaard
PhD student, MSc (pharm)
Odense University Hospital
Eligibility Criteria
Inclusion Criteria
- •Age: 18 years or older
- •Patient admitted or receiving ambulatory treatment for an acute transient ischemic attack or ischemic stroke which has occurred within the previous 30 days.
- •The patient or a carer usually dispenses the patient's medications
- •Written consent
Exclusion Criteria
- •Cognitive or physical impairment that would preclude comprehension of a conversation
- •Terminal illness
- •Lives in a care home or an institution
- •Receives dose dispensed medicine from a pharmacy
- •Medicine is dispensed by a nurse in the patient's home
- •Correctional mental health patients
Outcomes
Primary Outcomes
Medication Adherence to antiplatelets, anticoagulants and statins measured by proportion of days covered (PDC).
Time Frame: One year from inclusion
For antiplatelets, anticoagulants and statins: Percent of patients that are at least 80% adherent (PDC>0.8)
Time Frame: 1 year from inclusion
Secondary Outcomes
- Non-persistence with thromboprophylactic agents ( antiplatelets, anticoagulants, statins and antihypertensives) measured by percent of patients that are not supplied with medication for more than 3 continuous months(One year from inclusion)
- Accept rate for thromboprophylactic agents measured by percent of patients starting treatment within 0-90 days after discharge.(3 months from discharge)
- Composite endpoint: stroke, myocardial infarction or cardiovascular death(One year from inclusion)
- Medication Adherence to antihypertensives measured by proportion of days covered (PDC)(One year from inclusion)
- Percent of patients that are at least 80% adherent (PDC>0.8) to antihypertensives(One year from inclusion)