Pharmacist Intervention Programme to Improve Medication Adherence in Stroke Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 211
- 试验地点
- 2
- 主要终点
- Medication Adherence to antiplatelets, anticoagulants and statins measured by proportion of days covered (PDC).
研究概览
简要总结
Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group. The purpose of this study is to evaluate whether a complex tailored pharmacist intervention will lead to increased adherence to secondary stroke prevention medications and less new stroke events when compared to a usual care group. Interventions focus on motivational interviewing, medication review and telephone follow up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age: 18 years or older
- •Patient admitted or receiving ambulatory treatment for an acute transient ischemic attack or ischemic stroke which has occurred within the previous 30 days.
- •The patient or a carer usually dispenses the patient's medications
- •Written consent
排除标准
- •Cognitive or physical impairment that would preclude comprehension of a conversation
- •Terminal illness
- •Lives in a care home or an institution
- •Receives dose dispensed medicine from a pharmacy
- •Medicine is dispensed by a nurse in the patient's home
- •Correctional mental health patients
研究组 & 干预措施
Usual care
Usual care
干预措施: Usual care (Behavioral)
Complex tailored intervention
The intervention consists of 3 elements:
- Medication review with recommendations focused on antithrombotics and adherence to guidelines and patient´s adherence to medications.
- Discharge consultation with an pharmacist using motivational interviewing techniques.
- Follow-up telephone calls one week, two months and six months after discharge.
干预措施: Complex tailored intervention (Behavioral)
Complex tailored intervention
The intervention consists of 3 elements:
- Medication review with recommendations focused on antithrombotics and adherence to guidelines and patient´s adherence to medications.
- Discharge consultation with an pharmacist using motivational interviewing techniques.
- Follow-up telephone calls one week, two months and six months after discharge.
干预措施: Usual care (Behavioral)
结局指标
主要结局
Medication Adherence to antiplatelets, anticoagulants and statins measured by proportion of days covered (PDC).
时间窗: One year from inclusion
For antiplatelets, anticoagulants and statins: Percent of patients that are at least 80% adherent (PDC>0.8)
时间窗: 1 year from inclusion
次要结局
- Non-persistence with thromboprophylactic agents ( antiplatelets, anticoagulants, statins and antihypertensives) measured by percent of patients that are not supplied with medication for more than 3 continuous months(One year from inclusion)
- Accept rate for thromboprophylactic agents measured by percent of patients starting treatment within 0-90 days after discharge.(3 months from discharge)
- Composite endpoint: stroke, myocardial infarction or cardiovascular death(One year from inclusion)
- Medication Adherence to antihypertensives measured by proportion of days covered (PDC)(One year from inclusion)
- Percent of patients that are at least 80% adherent (PDC>0.8) to antihypertensives(One year from inclusion)
研究者
Ulla Hedegaard
PhD student, MSc (pharm)
Odense University Hospital