Systematic Follow up of Drug Treatment by Pharmacists in Secondary Prevention After Transient Ischemic Attack

Not Applicable

Completed

• Conditions: Stroke; Ischemic Attack, Transient
• Interventions: Behavioral: Drug use counselling

• Registration Number: NCT02089074
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

Use of drugs is an important factor in secondary prophylaxis after transient ischemic attack (TIA), but studies show that adherence to the prescribed drugs is often poor. This randomised controlled trial aims to investigate whether a systematic follow up of drug treatment using medication reconciliation, medication reviews and patient counselling by clinical pharmacists, improves adherence and/or decreases cardiovascular events the first three months and the first year after TIA. Patient satisfaction will also be compared between the two groups.

Detailed Description

Not available

Study Timeline

• Study Start: 2012-11
• Study First Submitted: 2014-03-13
• Study First Submitted QC: 2014-03-13
• Study First Posted: 2014-03-17
• Primary Completion: 2015-09
• Study Completion: 2016-06
• Status Verified: 2017-03
• Last Update Submitted: 2017-03-29
• Last Update Posted: 2017-03-30

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 265

Inclusion Criteria

• Probable or possible transient ischemic attack
• Residing in Central Norway
• Examined within 2 weeks after the onset of symptoms
• Modified Rankin Scale 3 or less and living at home
• enrolled in the MIDNOR-TIA study NCT02038725
• Informed consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
drug use counselling	Drug use counselling	Pharmacist conducting drug reconciliation, medication reviews and drug use counselling during hospitalisation. Follow up telephone calls 1 week, 1 month, 2 months and three months after discharge from hospital

Primary Outcome Measures

Name	Time	Method
adherence to drug treatment in secondary prevention after TIA	3 months	self reporting of adherence

Secondary Outcome Measures

Name	Time	Method
adherence to drug treatment in secondary prevention after TIA	1 year	self reporting of adherence
Incidence of stroke and cardiovascular events and deaths	1 year	Measured by using data from national health registries
patient satisfaction	1 year	Measured by using data from the Norwegian Stroke Registry
Persistence	1 year	Persistence measured by control of filled prescriptions
degree of disability or dependence in the daily activities	1 year	measured by modified Rankin Scale and indirectly by level of care

Trial Locations

Locations (6)

Levanger Sykehus; 🇳🇴 Levanger, Norway

Ålesund Sykehus; 🇳🇴 Ålesund, Norway

Kristiansund Sykehus; 🇳🇴 Kristiansund, Norway

Namsos Sykehus; 🇳🇴 Namsos, Norway

Molde Sykehus; 🇳🇴 Molde, Norway

St Olavs Hospital; 🇳🇴 Trondheim, Norway