JPRN-jRCTs071200019已完成2 期
A phase 2study of chemoradiation with use of weekly carboplatin and concurrent radiotherapy for local advanced non-small cell lung cancer in elderly patients - LOGIK1902
Harada Taishi0 个研究点目标入组 45 人开始时间: 2020年6月29日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 45
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 75age old 至 ot applicable（—）
- 性别
- All
入选标准
- •1)Patients with histologically or cytologically confirmed non-small cell lung cancer.
- •2)No prior history of chemotherapy, thoracic radiotherapy or surgical resection
- •3)Unresectable stage 3disease.
- •4)V20 is under 35%.
- •5)There is measurable region.
- •6)Age>=75
- •7)Eastern Cooperative Oncology Group performance status=<1
- •8)Leucocyte>=4000/mm3, Neutrocyte>=2000/mm3, platelets>=100000/mm3, hemoglobin>=9.0g/dl, AST and ALT=<100, bilirubin=<1.5mg/dl and serum creatinine=<1.5mg/dl. PaO2>=65torr or SpO2>=92%
- •9)Written informed consent.
排除标准
- •1)Involvement of contralateral hilar lymph nodes.
- •2)Interstitial pneumonia or pulmonary fibrosis detected with chest X-ray.
- •3)SVC syndrome.
- •4)Obstructive pneumonia or active severe infection.
- •5)Other active invasive malignancies
- •6)Severe complications such as gastrointestinal bleeding, significant heart failure or uncontrolled diabetes and so on.
- •7)History of severe hypersensitivity.
- •8)Regular use of corticosteroids.
- •9)Mental illness
- •10)Pregnant woman and lactating woman
- •11)Active hepatitis B
- •12)A case considered by an investigator inadequate for the trial.
研究者
相似试验
已完成
不适用
A phase II study of definitive chemoradiation therapy using docetaxel, nedaplatin, and 5-fluorouracil with modified dose radiation (mDNF-R) followed by S-1 maintenance therapy and salvage therapy for patients with clinical stage IB-IIIC (non-T4) esophageal carcinomaEsophageal carcinomaJPRN-UMIN000025109Sapporo Medical University School of Medicine, Department of Medical Oncology24
已完成
2 期
A phase II study of chemoradiotherapy with use of involved-field conformal radiotherapy and accelerated hyperfractionation for Stage III non-small cell lung cancerStage III non-small cell lung cancerJPRN-UMIN000010428West Japan Oncology Group44
已完成
1 期
A phase I/II study of chemoradiation with use of carboplatin/nab-paclitaxel and concurrent radiotherapy for local advanced non-small cell lung cancerJPRN-UMIN000012719Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University56
已完成
2 期
Preoperative chemoradiation with UFT-E plue leucovorin and translational study for locally advanced rectal cancerocally advanced rectal cancer (cT3-4, Nx, M0)CancerISRCTN11812525ational Cancer Center121
进行中（未招募）
2 期
Phase II study of definitive chemoradiotherapy with S-1 plus cisplatin for clinical stage IA esophageal squamous cell carcinoma. (SP-RT)Esophageal cancerJPRN-jRCTs051180078Yamamoto Sachiko76