ACTRN12622001166763
Completed
未知
Does anterior cruciate ligament (ACL) injury impair the molecular pathways responsible for building muscle?
Assoc Prof David Opar0 sites12 target enrollmentAugust 24, 2022
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Anterior Cruciate Ligament injury
- Sponsor
- Assoc Prof David Opar
- Enrollment
- 12
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\.Male or female
- •2\.Aged between 18 to 35 years
- •3\.One leg sustained an ACL injury within the last 5\-years, but can safely complete lower limb strength training
- •4\.BMI 18\.5\-29\.9m2
Exclusion Criteria
- •1\.Any lower limb injury in the past 24\-months that influences the quadriceps responses to exercise (e.g. muscle strain)
- •2\.Known cardiovascular disease or diabetes
- •3\.Known bleeding disorder (i.e. hemophilia A \[factor VIII deficiency], hemophilia B \[factor IX deficiency], von Willebrand disease, or other rare factor deficiencies including I, II, V, VII, X, XI, XII and XIII)
- •4\.Major or chronic illness that impairs mobility or eating/digestion
- •5\.Taking prescription medications (i.e. beta\-blockers, anti\-arrhythmic drugs, statins, insulin sensitising drugs, or drugs that increase the risk of bleeding \[i.e. anticoagulants, antiplatelets, novel oral anticoagulants \[NOAs], nonsteroidal anti\-inflammatory drugs \[NSAIDs], selective norepinephrine reuptake inhibitors \[SNRI], or selective serotonin reuptake inhibitors \[SSRIs])
Outcomes
Primary Outcomes
Not specified
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