Remineralization Effect of Eggshell Powder on Post-orthodontic White Spot Lesions Compared to CPP-ACP

Not Applicable

• Conditions: Dental Caries
• Interventions: Other: Eggshell powder gel; Other: CPP-ACP crème

• Registration Number: NCT03963791
• Lead Sponsor: Cairo University

Brief Summary

This research is conducted to compare the remineralization efficacy of eggshell powder gel and CPP-ACP (MI paste) on post-orthodontic white spot lesions.

Detailed Description

Not available

Study Timeline

• Status Verified: 2019-05
• Study First Submitted: 2019-05-15
• Study First Submitted QC: 2019-05-22
• Last Update Submitted: 2019-05-22
• Study First Posted: 2019-05-28
• Last Update Posted: 2019-05-28
• Study Start: 2019-10-05
• Primary Completion: 2020-04-05
• Study Completion: 2020-06-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• A patient who has just completed a comprehensive orthodontic treatment.
• Presence of at least one WSL, DIAGNOdent score (0-20).
• Age range between 13 and 35years.

Exclusion Criteria

• Patients are unable to return for recall appointments.
• High caries risk.
• Have plaque accumulation and a periodontal problem
• In progress treatment of chronic disease.
• Presence of abnormal oral, medical, or mental condition (including any milk-related allergies or any medical condition involving kidneys or salivary glands).
• Presence of dentin caries, enamel hypoplasia or restorations on maxillary anterior teeth.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Eggshell powder gel	CPP-ACP crème	prepared from eggshell powder. applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.
Eggshell powder gel	Eggshell powder gel	prepared from eggshell powder. applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.
CPP-ACP crème	Eggshell powder gel	CPP-ACP crème (GC Tooth Mousse). applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.
CPP-ACP crème	CPP-ACP crème	CPP-ACP crème (GC Tooth Mousse). applied on the tooth surfaces twice daily (after breakfast and before bedtime) after brushing the teeth.

Primary Outcome Measures

Name	Time	Method
white spot lesion progression.	6 months.	The change in the lesion fluorescence will be evaluated using diode laser fluorescence device (Diagnodent).

Trial Locations

Locations (1)

Cairo univercity; 🇪🇬 Cairo, Egypt