Sleep neuroimaging: towards the neurobiology characterization of human REM sleep

Recruiting

Conditions: n.a
neuroscientific research

Registration Number: NL-OMON48306

Lead Sponsor: Radboud Universiteit Nijmegen

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 28

Inclusion Criteria

18 to 40 years old
right handed

Exclusion Criteria

1) Metal parts, that cannot be removed, are present in or on your upper body,
e.g. plates, screws, aneurysm
clips, metal splinters, piercings or medical plasters. Dental fillings, crowns,
a metal wire behind the teeth, tattoos
and contraceptive coils are allowed. The researcher will additionally inform
you.
2) Clothing on the upper body containing any metal e.g. zips, buttons, hooks,
braces, metal yarn (LUREX). This
also applies to bras containing a metal brace wire.
3) You have an active implant, a pacemaker, insulin pump, neurostimulator
and/or ossicle prosthesis.
4) You have a history of brain surgery.
5) You suffer from epilepsy.
6) You suffer from claustrophobia.

Study & Design

Study Type: Observational non invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>The main endpoints of this study are the blood level-dependent (BOLD) response<br /><br>and the EEG signal as dependent variables. We want to investigate brain<br /><br>connectivity on regions of interest for neurobiological models of dreaming such<br /><br>as the vmPFC, dlPFC, and hippocampus for instance. Brain networks during<br /><br>non-lucid, lucid REM sleep compared with wakefulness. Additionally, we are<br /><br>interested in EEG frequency characterization and regional activities during REM<br /><br>sleep.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary aims of the proposed research include EEG correlates of lucid REM and<br /><br>non-lucid REM sleep, activity associated with tonic and phasic REM sleep that<br /><br>is theta, alpha, and gamma bands, REM saccades, and its activation association. </p><br>