Comparison of reduction of blood loss at myomectomy using Misoprostol to that of Haemostatic Torniquet

Not Applicable

• Conditions: Fertility-female; Uterine Fibroid

• Registration Number: PACTR201802003039106
• Lead Sponsor: niversity of Ilorin Teaching Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-02-02
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 80

Inclusion Criteria

Diagnosis of uterine fibroid with a treatment plan for abdominal myomectomy

Exclusion Criteria

1.Known allergy to prostaglandins including misoprostol.
2.Chronic medical disorders including hypertension, diabetes mellitus, cardiac or pulmonary diseases.
3.Previous uterine surgery (myomectomy or caesarean section).
4.Known bleeding or clotting disorders.
5.Haematocrit at 24hours before surgery less than 30%.
6.Patient refusal to participate in the study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Intra-operative blood loss andNeed for intra-operative blood transfusion.

Secondary Outcome Measures

Name	Time	Method
1. Occurrences of side effects of Misoprostol including nausea, vomiting, diarrhoea, shivering and elevated temperature (temperature ¿ 380C). 2.Need for hysterectomy. 3.Post-operative haematocrit. 4.Need for post-operative blood transfusion.