Research for key technology and applications for catheter ablation of ventricular arrhythmias guided by noninvasive three-dimensional electrocardiographic mapping
- Conditions
- ventricular arrhythmias
- Registration Number
- ITMCTR1900002554
- Lead Sponsor
- First Affiliated Hospital of Zhejiang Chinese Medical University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
1. Patients diagnosed with premature ventricular contractions (PVCs) and ventricular tachycardia (VT);
2. Patients aged between 18 and 80 years;
3. Patients with obvious symptoms of PVCs/VT but cannot be relieved or tolerate antiarrhythmic medicine;
4. Impaired left ventricular function or tachycardia-induced cardiomyopathy due to asymptomatic PVCs/VT;
5. Frequent monomorphic PVCs/VT (>10000 per 24 h or burden >10%);
6. Informed consent can be obtained.
1. Failure or abandonment of the ablation procedure;
2. Sustained ventricular tachycardia, Torsade de pointes, ventricular flutter or ventricular fibrillation;
3. PVCs/VT due to reversible reasons (electrolyte disturbance, acute ischemia, hyperthyroidism, etc);
4. Infrequent monomorphic PVCs(<10000 per 24 h);
5. blood clots in the heart;
6. Acute myocardial infarction(within 2 months);
7. NYHA cardiac functional grading>=level III;
8. Other severe cardiac dysfunction, cardiac ion channel diseases, inherited arrhythmogenic diseases and so on;
9. complicated with other severe diseases (e.g. hepatic and renal dysfunction, malignant tumor);
10. pregnancy or be allergic to iodic contrast medium.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method acute successful rate;whole fluoroscopic exposure;total procedure time;
- Secondary Outcome Measures
Name Time Method long-term success rate;mapping accuracy;