NCT05921682招募中不适用
Early Body Temperature Targets and Relationship With Prognosis in Patients With Heat Stroke
Second Affiliated Hospital, School of Medicine, Zhejiang University6 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2023年5月28日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 200
- 试验地点
- 6
- 主要终点
- mortality
研究概览
简要总结
The goal of this observational study is to explore the optimal target body temperature in first 24 hours and the relationship between body temperature and adverse outcomes of heat stroke.
The main questions it aims to answer are:
- the optimal target body temperature at 0.5 h, 2 h, and the lowest body temperature of heat stroke.
- the best body temperature at the cutting point of stop cooling.
- The relationship between the volume and speed of ice saline infusion and the cooling effect.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •≥ 18 years; ② diagnosed as heat stroke; ③ Informed consent from patients or family members.
排除标准
- •need immediate cardiopulmonary resuscitation; ② transferred from another hospital; ③ with severe underlying organ insufficiency; ④ pregnant women.
结局指标
主要结局
mortality
时间窗: up to 90 days
Number of participants who dead during hospitalization
organ damage
时间窗: up to 90 days
Number of participants with organ damage, including but not limited to brain, lung, heart, kidney, liver and coagulation
次要结局
- continuous renal replacement therapy(up to 90 days)
- length of ICU stay(up to 90 days)
- length of hospital stay(up to 90 days)
研究者
研究点 (6)
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