Relationship Between Postoperative Tempeartive and Acute Kidney Injury

Active, not recruiting

• Conditions: Patients Undergoing Valvular Heart Surgery

• Registration Number: NCT06647771
• Lead Sponsor: Yonsei University

Brief Summary

The investigators aimed to identify body temperature trajectory classes based on core temperature changes during the first 12 hours post-surgery and to explore their relationship with postoperative acute kidney injury in patients undergoing valvular heart surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-12
• Status Verified: 2024-10
• Study First Submitted: 2024-10-13
• Study First Submitted QC: 2024-10-16
• Last Update Submitted: 2024-10-16
• Study First Posted: 2024-10-18
• Last Update Posted: 2024-10-18
• Primary Completion: 2026-08-11
• Study Completion: 2026-08-11

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 3274

Inclusion Criteria

• Patients who underwent valvular heart surgery between January 2016 and July 2023 at Severance Cardiovascular Hospital of Yonsei University Health System

Exclusion Criteria

• Patients who underwent the same surgery within 30 days,
• Patients with less than two temperature measurements within 12 hours after surgery, - Patients with missing creatinine test values before and within seven days after surgery,
• Patients who died during surgery

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
acute kidney injury ≥ stage 2 according to the KDIGO criteria	seven days after valvular heart surgery	According to the KDIGO criteria, postoperative acute kidney injury of stage 2 or higher was defined as a 100% increase in creatinine within the first seven days after surgery. The association between stage 2-3 acute kidney injury and postoperative body temperature trajectory classes was investigated.

Secondary Outcome Measures

Name	Time	Method
non-recovery from acute kidney injury within 48	72 hours after the onset of acute kidney injury	The association between postoperative body temperature trajectory classes and non-recovery from acute kidney injury was investigated at two time points: within 48 hours
non-recovery from acute kidney injury within 72 hours	72 hours after the onset of acute kidney injury	The association between postoperative body temperature trajectory classes and non-recovery from acute kidney injury was investigated at two time points: within 72 hours.

Trial Locations

Locations (1)

Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine; 🇰🇷 Seoul, Korea, Republic of