Effects of serial whole body cryotherapy on disease activity, functional health, cytokines and marker of bone and cartilage metabolism in rheumatoid diseases, e.g, rheumatoid arthritis, psoriatic arthritis, axial spondyloarthritis and primary fibromyalgia, and healthy individuals
- Conditions
- M06.80M05.8M45.0L40.5M79Other seropositive rheumatoid arthritisArthropathic psoriasisOther soft tissue disorders, not elsewhere classified
- Registration Number
- DRKS00021218
- Lead Sponsor
- Campus Kerckhoff der Justus-Liebig-Universität Gießen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 192
confirmed rheumatoid arthritis according to the ACR/EULAR classification criteria of rheumatoid arthritis of 2010
- confirmed psoriatic arthritis according to the CASPAR criteria
- confirmed axial spondylarthritis / ankylosing arthritis according to the ASAS classification criteria
- confirmed primary fibromyalgia according to the ACR/EULAR criteria of 2010 and the modification of 2011
- Health control subjects after medical examination
- Written consent and approval of the study
- stable medication (antirheumatic as well as analgesic and other basic medication) 4 weeks before starting the study and during the entire study
Contraindications for whole-body cold therapy treatment (cryoglobulins, cold urticaria, vasculitis, Raynaud's syndrome, unstable arterial hypertension, peripheral arterial circulatory disorders, cold hypersensitivity, disturbed temperature sensation, bladder and kidney diseases, etc.) .
No written consent.
No comprehension of the study.
Lack of German knowledge.
Presence of an accompanying secondary pain syndrome in patients with inflammatory rheumatic diseases (RA, PsA, axSpA)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method