Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery
Not Applicable
Completed
- Conditions
- Post Partum Hemorrhage
- Interventions
- Other: delayed cord clamping
- Registration Number
- NCT04353544
- Lead Sponsor
- Federico II University
- Brief Summary
Policies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds aLer birth, whereas latercord clamping usually involves clamping the umbilical cord greater than one minute after the birth or when cord pulsation has ceased
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 122
Inclusion Criteria
- singleton pregnancy
- at term
- cephalic presentation
- spontaneous labor
- spontaneous vaginal delivery
Exclusion Criteria
- multiple gestation
- preterm gestation
- induced labor
- operative delivery
- hypertension or preeclampsia
- fetal anomaly
- abnormal placentation
- planned cord blood banking
- maternal bleeding disorder
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Immediate cord clamping delayed cord clamping Immediate cord clamping was defined as clampingwithin 15 seconds of birth delayed cord clamping delayed cord clamping when the cord stopped pulsing, or five minutes
- Primary Outcome Measures
Name Time Method change in maternal hemoglobin level on post delivery day 1 compared with the predelivery hemoglobin level day 1 after delivery The primary outcome was an objective measure of maternal blood loss: the change in maternal hemoglobin level on postdelivery day 1 compared with the predelivery hemoglobin level.
- Secondary Outcome Measures
Name Time Method uterotonic administration at the time of delivery jaundice day 10 of life neonatal jaundice
need for blood transfusion at the time of delivery postpartum hemorrhage at the time of delivery defined as estimated blood loss\>500cc
Trial Locations
- Locations (1)
Casa di Cura Accreditata Fabia Mater, Rome, Italy
🇮🇹Rome, Roma, Italy