The effect of emergency department pharmacists on drug overuse and drug underuse in patients with an adverse drug event (ADE)-related hospitalisatio

Not Applicable

Completed

• Conditions: Patients visiting the emergency department with an adverse drug event; Injury, Occupational Diseases, Poisoning

• Registration Number: ISRCTN12506329
• Lead Sponsor: Erasmus MC

Brief Summary

2022 Results article in https://doi.org/10.1186/s12913-022-08696-7 (added 22/05/2023) 2024 Results article in https://pubmed.ncbi.nlm.nih.gov/39180043/ cost study (added 27/08/2024)

Detailed Description

Not available

Study Timeline

• Study Completion: 2018-01-01
• Study Start: 2022-03-06
• Last Update Posted: 9 September 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 216

Inclusion Criteria

Patients aged 18 years and older were eligible for inclusion if they were hospitalised for more than 24 hours after visiting the ED.

Exclusion Criteria

1. No communication possible due to condition or language barrier
2. Cognitive impairment; transfers to other hospital
3. No pre-admission medication; admission due to problems with cancer treatment
4. Alcohol intoxication and/or (self)poisoning related hospitalisation
5. Psychiatric hospitalisation
6. Intensive care unit (ICU) hospitalisation
7. Foreign tourist or homeless patient
8. Already included patient readmitted within the research period
9. Patients with no informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The number of medication changes for drug overuse and drug underuse that took place during hospital admission and persisted six months thereafter measured using medication overviews and estimate the difference between groups with poisson regression analysis.