NCT01083719Unknown2 期
Phase II Study Comparing FDG-PET Versus MRI Based Target Volume Delineation in Glioblastoma and the Role of FDG-PET/CT in the Alteration of MRI Based Target Volumes.
Medanta Institute of Clinical Research0 个研究点目标入组 15 人开始时间: 2010年4月1日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 发起方
- 入组人数
- 15
- 主要终点
- Tumor infiltration defined on FDG-PET not determined to MRI
研究概览
简要总结
HYPOTHESIS AND SAMPLE SIZE The tumor delineated by FDG-PET is significantly different from the delineation achieved by MR T1 contrast weighted images in glioblastoma; expecting a standard error of 12.5 % (a confidence interval of 25%), with a confidence level set at 95%, a sample size of 15 patients would be accrued in the study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Post operative patients of documented high grade gliomas (grade III and IV)
- •Patients who have not undergone any previous irradiation to brain.
- •Performance Scale as defined by ECOG PS 0-3
排除标准
- •Patients who are diabetic.
- •Patients who are pregnant.
- •Any documented contrast allergy to the agents used for imaging.
- •Patients who are unable to comprehend or cooperate effectively for treatment planning.
结局指标
主要结局
Tumor infiltration defined on FDG-PET not determined to MRI
时间窗: 18 months
次要结局
未报告次要终点
研究者
相似试验
招募中
2 期
FDG-PET-Guided Metastasis Directed Radiation Therapy for the Treatment of Metastatic Hormone Sensitive Prostate Cancer, The PRTY TrialCastration-Sensitive Prostate CarcinomaMetastatic Prostate CarcinomaStage IVB Prostate Cancer AJCC v8NCT06244004Northwestern University125
招募中
不适用
iver MaP - A Pilot Study of FDGal-PET and Dynamic MRI Evaluation of Regional Liver Function in Patients with Liver Cancer Undergoing Surgery or Stereotactic Radiation Therapy.ACTRN12619001499178Metro South Hospital and Health Services (Princess Alexandra Hospital)20
终止
不适用
Comparison Between FDG-PET and MRI for the Assessment of Response to Intensive Chemotherapy in Multiple Myeloma Patients.Multiple MyelomaNCT00200668Nantes University Hospital
尚未招募
不适用
Validation of FDG-PET segmentation tools for tumor delineation by correlation of CT- and PET volume measurements with histopathology of nodal metastases of head and neck carcinomas.plaveiselcelcarcinomen uitgaande van cavum oris, oropharynx, hypopharynx, larynxhead and neck cancersquamous cell carcinoma of head and neck1001799010029107NL-OMON32216niversitair Medisch Centrum Sint Radboud15
Unknown
不适用
Validation of FDG-PET Segmentation Tools for Tumor Delineation by Correlation of CT- and FDG-PET Volume Measurements With Histopathology of Nodal Metastases of Head and Neck Carcinomas.Head and Neck CancerNCT00782691Radboud University Medical Center15