Validation of FDG-PET Segmentation Tools for Tumor Delineation by Correlation of CT- and FDG-PET Volume Measurements With Histopathology of Nodal Metastases of Head and Neck Carcinomas.

• Conditions: Head and Neck Cancer
• Interventions: Other: CT-FDG/PET scan of the head-and-neck region

• Registration Number: NCT00782691
• Lead Sponsor: Radboud University Medical Center

Brief Summary

Various methods of FDG-PET signal segmentation will be validated by correlation of histopathologically measured tumor dimensions in lymph node dissection specimens of head-and-neck cancer patients.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-07
• Status Verified: 2008-10
• Study First Submitted: 2008-10-29
• Study First Submitted QC: 2008-10-29
• Last Update Submitted: 2008-10-29
• Study First Posted: 2008-10-31
• Last Update Posted: 2008-10-31
• Primary Completion: 2009-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 15

Inclusion Criteria

• All patients with N+ squamous cell carcinoma of the head and neck, planned for neck dissection.
• Age >18 years.

Exclusion Criteria

• Pregnancy.
• Women breast feeding

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Head-and-neck cancer patients.	CT-FDG/PET scan of the head-and-neck region	Head-and-neck cancer patients eligible for therapeutic lymph node dissection of cervical nodes.

Primary Outcome Measures

Name	Time	Method
How accurate are the various FDG-PET segmentation tools?	Measurements are performed in conjunction with the clinical pathologist directly postoperatively.

Trial Locations

Locations (1)

Radboud University Nijmegen Medical Centre; 🇳🇱 Nijmegen, Gelderland, Netherlands