Oncologic Outcomes Based on Clinical Pattern of Preoperative PET-CT in Resected Pancreatic Cancer-Prospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Clinical PET type assessed by surgeons from preoperatively preformed PET imaging
研究概览
简要总结
The 18F-FDG-PET scan is currently being used for cancer diagnosis, staging, identifying hidden metastasis, and assessment of treatment responses in clinical oncology. Although there are important studies suggesting potential associations between PET-based parameters and oncologic outcomes, the calculation and official documentation of individual PET-based parameters might not be routine in clinical practice because these processes usually require time- and labor-consuming processes for the radiologists. In this study, the investigators prospectively determined clinical 18F-FDG-PET type according to degree of FDG-uptake in pancreatic cancer and compare oncologic outcomes between the types.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Candidate for radical pancreatectomy due to pancreatic cancer without neoadjuvant treatment
- •Age between 20 years old and 80 years old
- •General performance status greater than 70
- •Results of peroperative PET-CT available
排除标准
- •Unresectable, locally advance and metastatic pancreatic cancer
- •Patients not wanting operation
- •ASA score of greater than 3
- •History of chronic alcoholism ot drug abuse
- •Lack of patient compliance
- •Patients not agreeing to enroll in the study.
- •Patients unable to understand and sign the study agreement.
- •History of neoadjuvant treatment
结局指标
主要结局
Clinical PET type assessed by surgeons from preoperatively preformed PET imaging
时间窗: 1 week after surgery
Three surgeons will review the preoperative PET imaging and each will determine the clinical PET type as either K-type or Non-K type. Inter-surgeon agreement of clinical PET type will be determined. Clinicopathologic characteristics between K-type and Non-K type will also be analyzed.
次要结局
- Number of patients with recurrence of cancer or mortality from cancer following operation(3 years)