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临床试验/NCT07420933
NCT07420933
已完成
不适用

The Effect of Pea Protein Supplementation on Muscle Hypertrophy and Metabolic Parameters in Young Adults Following an 8-week Resistance Training Program

Texas Woman's University1 个研究点 分布在 1 个国家目标入组 34 人开始时间: 2024年2月3日最近更新:

概览

阶段
不适用
状态
已完成
入组人数
34
试验地点
1
主要终点
Difference in body composition

概览

简要总结

The goal of this clinical trial is to compare the impact of pea protein or whey protein supplementation during a progressive resistance exercise (PRE) regimen on body composition and strength in young adults who are not undergoing regular strength training. The main questions it aims to answer are:

  1. Do lean body mass changes differ between supplement groups following a progressive resistance exercise PRE training program?
  2. Does improvements in muscle strength differ between groups following a PRE training program?
  3. Does glucose, insulin, and essential amino acid appearance and clearance rate differ between groups following a PRE training program? Researchers will compare pea protein supplementation to whey protein supplementation to see if there are any differences in body composition and strength

Participants will:

  • Consume Pea or Whey protein supplement twice daily for 8 weeks
  • Participate in a PRE training program twice weekly for approximately 1.5 hours per day

详细描述

Adequate dietary protein intake is essential for maximizing skeletal muscle hypertrophy and strength gains during progressive resistance exercise (PRE) training. Whey protein isolate is commonly used to support these adaptations; however, there is limited clinical evidence comparing plant-based protein supplements with whey protein when protein dose is controlled and combined with structured resistance training. Pea protein isolate represents a sustainable, plant-based alternative, but its effectiveness in promoting muscle accretion, strength, and metabolic responses relative to whey protein isolate has not been fully characterized. Therefore, this study will compare the effects of pea protein isolate and whey protein isolate supplementation on changes in lean body mass, muscle strength, and postprandial metabolic responses in healthy, untrained young adult males. Participants will be randomized in a double-blind, parallel-group design to consume either pea protein isolate or whey protein isolate for 8 weeks while completing a supervised, PRE training program. Lean body mass and strength outcomes will be assessed before and after the intervention, and acute postprandial essential amino acid, glucose, and insulin responses will be evaluated following standardized protein ingestion at baseline and post-intervention.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Triple (Participant, Investigator, Outcomes Assessor)

入排标准

年龄范围
18 Years 至 30 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • Healthy Adults 18-30y
  • BMI between 18.5 - 28 kg/m\*\*2
  • The subjects will be excluded if:
  • they have a history or current diagnosis of cardiovascular disease, cancer, diabetes, gastrointestinal disorders, or metabolic disorders.
  • they use tobacco products
  • consume alcohol as defined as \>2 drinks per day,
  • follow a special diet
  • reported recent significant body weight changes (\>5% prior 3 months)
  • report an intolerance or allergy to ingredients in the supplements.
  • report regular consumption of other muscle or metabolic stimulating products or drugs such as creatine, other amino acids or protein supplements, growth hormone or derivatives, or ergogenic aids including steroids.

排除标准

  • 未提供

研究组 & 干预措施

Pea Protein

Experimental

Participants in this arm will consume pea protein isolate (24g/sachet) twice daily for 8 weeks while participating in an 8-week PRE program (2, 1.5hr sessions per week)

干预措施: Protein Isolate (Dietary Supplement)

Pea Protein

Experimental

Participants in this arm will consume pea protein isolate (24g/sachet) twice daily for 8 weeks while participating in an 8-week PRE program (2, 1.5hr sessions per week)

干预措施: Progressive Resistance Exercise Training (PRE) (Behavioral)

Whey Protein

Active Comparator

Participants in this arm will consume whey protein isolate (24g/sachet) twice daily for 8 weeks while participating in an 8-week PRE program (2, 1.5hr sessions per week)

干预措施: Protein Isolate (Dietary Supplement)

Whey Protein

Active Comparator

Participants in this arm will consume whey protein isolate (24g/sachet) twice daily for 8 weeks while participating in an 8-week PRE program (2, 1.5hr sessions per week)

干预措施: Progressive Resistance Exercise Training (PRE) (Behavioral)

结局指标

主要结局

Difference in body composition

时间窗: Baseline and 8 weeks

Differences in lean mass (kg, kg/m\^2, and % total mass) and fat mass (kg, and % total mass) assessed using Dual Energy X-ray Absorptiometry (DXA; Horizon W, Hologic, Marlborough, MA)

Difference in muscle strength

时间窗: Baseline and 8 weeks

Differences in muscle strength assessed by maximal isometric force produced by quadriceps (Nm) using a Biodex System 3 dynamometer, hand grip (kg) using a handgrip dynamometer, 1-Rep Max for chest press (kg), and 1-Rep Max for leg press (kg)

次要结局

  • Nutritional Metabolic Biomarkers(Baseline and 8 weeks)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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