A PROSPECTIVE OBSERVATIONAL STUDY TO STUDY THE EFFECT OF PROPOFOL ANAESTHESIA ON CEREBRAL HEMODYNAMICS IN INFANT UNDERGOING INGUINAL HERNIA REPAIR SURGERY
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 64
- 试验地点
- 1
- 主要终点
- CORELATION OF MEAN ARTERIAL PRESSURE AND MFV MEAN FLOW VELOCITY ANTERIOR CEREBRAL ARTERY
研究概览
简要总结
Infants undergoing surgery under general anaesthesia are at increased risk of subsequent neurodevelopmental delay. One mechanism contributing to such delay may be disturbances in cerebral perfusion during general anesthesia.This is due to impaired cerebral auto regulation leading to a pressure-passive cerebral circulation and reduced ability to maintain stable cerebral perfusion during general an aesthesia.Propofol is a common anaesthesia agent used for induction and maintenance of anaesthesia. The relation of change in mean arterial pressure and corresponding change in cerebral perfusion is not completely understood under propofol anaesthesia. The purpose of this study is to assess the impact of propofol anaesthesia on cerebral hemodynamic in infants undergoing inguinal hernia repair surgery, using brain Doppler sonography.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 1.00 Month(s) 至 12.00 Month(s)（—）
- 性别
- All
入选标准
- •INFANT UNDERGOING ELECTIVE INGUINAL HERNIA REPAIR SURGERY UNDER GENERAL ANAESTHESIA AMERICAN SOCIETY OF ANAESTHESOLOGISTS (ASA 1 AND 2 ) PHYSICAL STATUS.
排除标准
- •CARDIOVASCULAR OR NEUROLOGICAL DISEASE HISTORY OF PREMATURE BIRTH.
结局指标
主要结局
CORELATION OF MEAN ARTERIAL PRESSURE AND MFV MEAN FLOW VELOCITY ANTERIOR CEREBRAL ARTERY
时间窗: BASELINE BEFORE PREOXYGENATION | EVERY 5 MINUTES FROM BASELINE TILL SHIFTING THE INFANT TO POST OPERATIVE WARD
USING DOPPLER SONOGRAPHY THROUGH ANTERIOR FONTANELLE DURING PROPOFOL ANESTHESIA
时间窗: BASELINE BEFORE PREOXYGENATION | EVERY 5 MINUTES FROM BASELINE TILL SHIFTING THE INFANT TO POST OPERATIVE WARD
次要结局
- TO DETERMINE THE EFFECTS OF PROPOFOL ANAESTHESIA ON PSV DFV PI AND RESISTIVE INDEX(BASELINE BEFORE PREOXYGENATION)
研究者
DR SAMIKSHA PARASHAR
Dr.Ram Manohar Lohia Institute of Medical Sciences VIBHUTI KHAND LUCKNOW