Comparing Pain Relief Between Exparel® Injection vs. On-Q Catheter as the Postsurgical Analgesia Following Total Knee Arthroplasty (TKA)

Not Applicable

Completed

• Conditions: Osteoarthritis: Joint Replacement Surgery
• Interventions: Drug: On-Q pain intra-articular catheter; Drug: Exparel

• Registration Number: NCT02739230
• Lead Sponsor: Rothman Institute Orthopaedics

Brief Summary

The goal of this research project is to evaluate the effectiveness of a novel treatment to control pain after Total Knee Arthroplasty (TKA). The proposed approach to manage pain and eliminate risks associated with catheters is the use of Exparel injection into the joint at the time of surgery.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-12
• Primary Completion: 2015-10
• Status Verified: 2016-04
• Study First Submitted: 2016-04-07
• Study First Submitted QC: 2016-04-14
• Last Update Submitted: 2016-04-14
• Study First Posted: 2016-04-15
• Last Update Posted: 2016-04-15

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. Adults scheduled to undergo primary total knee replacement
2. Willing and able to provide informed consent

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
On-Q intraarthicual catheter placement	On-Q pain intra-articular catheter	-
Exparel Injection	Exparel	-

Primary Outcome Measures

Name	Time	Method
Total Morphine and morphine equivalent consumption	96 hours post-op