A Worldwide Cancer Registry Enrolling Participants Profiled With a Next-Generation Sequencing Test

Recruiting

• Conditions: Solid Tumours

• Registration Number: NCT04529122
• Lead Sponsor: Hoffmann-La Roche

Brief Summary

WAYFIND-R is a registry that aims to capture high-quality real-world data linking next-generation sequencing, treatments and outcomes from cancer patients diagnosed with a solid tumour. The WAYFIND-R has three main overarching objectives: 1. To provide a platform to support the design and conduct of clinical and epidemiological research; 2. To develop an evidence-generation platform to better understand health outcomes and cancer care processes; and 3. To characterize the treatments and clinical course of solid tumor cancers in patients who have undergone NGS testing.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2020-08-25
• Study First Submitted QC: 2020-08-25
• Study Start: 2020-08-27
• Study First Posted: 2020-08-27
• Status Verified: 2025-08
• Last Update Submitted: 2025-08-01
• Last Update Posted: 2025-08-03
• Primary Completion: 2026-12-31
• Study Completion: 2026-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 15000

Inclusion Criteria

• Participant is an adult (according to the age of majority as defined by local regulations)
• Participant is currently diagnosed with any type of solid tumour cancer, at any stage of the disease, at the enrollment date (informed consent date)
• Participant has undergone NGS testing, no longer than 3 months prior to the enrollment date, irrespective of the availability of test results
• Informed consent has been obtained from the participant or legally authorized representative, as per local regulations

Exclusion Criteria

-Participant has a prior or current diagnosis of haematological malignancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Overall Survival	From date of registry entry until death, for up to 5 years

Trial Locations

Locations (134)

Instituto Alexander Fleming; 🇦🇷 Buenos Aires, Argentina

CEMIC; 🇦🇷 Buenos Aires, Argentina

Lkh-Univ. Klinikum Graz; 🇦🇹 Graz, Austria

Hospital Moinhos de Vento; 🇧🇷 Porto Alegre, Rio Grande Do Sul, Brazil

Instituto do Cancer do Estado de Sao Paulo - ICESP; 🇧🇷 Sao Paulo, São Paulo, Brazil

Hospital Alemao Oswaldo Cruz; 🇧🇷 Sao Paulo, São Paulo, Brazil

D'or Instituto de Pesquisa e Educação; 🇧🇷 Rio de Janeiro, Brazil

Beneficencia Portuguesa de Sao Paulo; 🇧🇷 São Paulo, Brazil

Alberta Health Services; 🇨🇦 Calgary, Alberta, Canada

The Ottawa Hospital - General Campus; 🇨🇦 Ottawa, Ontario, Canada

Scroll for more (124 remaining)