The Effect of High Flow Nasal Oxygenation on Gastric Insufflation in Paralyzed Anesthetized Patients Undergoing Laryngologic Surgery
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 45
- Locations
- 2
- Primary Endpoint
- change of gastric volume
Study Overview
Brief Summary
Transnasal humidified rapid-insufflation ventilatory exchange(THRIVE), or also termed high flow nasal oxygenation (HFNO) is a method of supplying heated, humidified high concentrations of oxygen via nasal cavity.
The purpose of this study is to investigate the effect of HFNO on gastric insufflation in paralyzed anesthetized patients undergoing laryngologic surgery.
Detailed Description
HFNO can be used during intraoperative period. HFNO reduces the risk of desaturation and prolongs the safe apnea time, compared with conventional oxygenation.
In laryngeal microsurgery, HFNO therapy make possible to perform tubeless anesthesia, providing perfect exposure of structure of the vocal cords.
HFNO have a risk for low level of positive pressure can make gastric distension, but gastric reflux or aspiration were not occurred during rapid sequence induction for emergency operation.
The purpose of this study is to investigate the effect of HFNO on gastric insufflation in paralyzed anesthetized patients undergoing laryngologic surgery.
Study Design
- Study Type
- Interventional
- Allocation
- Na
- Intervention Model
- Single Group
- Primary Purpose
- Diagnostic
- Masking
- None
Eligibility Criteria
- Ages
- 19 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •American Society of Anesthesiology physical status classification I and II
- •Patients scheduled for laryngeal microsurgery under general anesthesia
Exclusion Criteria
- •gastroesophageal reflux
- •gastric pathology
- •pregnancy
- •major cardiovascular, pulmonary, or cerebrovascular disease
- •severe obesity (body mass index>35 kg/m2)
Outcomes
Primary Outcomes
change of gastric volume
Time Frame: before HFNO application (baseline), immediately after HFNO application
Ultrasound exam will measure the antral cross-sectional area of gastric antrum
Secondary Outcomes
No secondary outcomes reported
Investigators
Jong Yeop Kim
Professor
Ajou University School of Medicine