Role of Insulin like growth factor 1 (IGF-1), TNF alpha, Interleukin 6 and hs-CRP in different grades of Diabetic Foot Ulcer - NI

Dr Shaheen B Shaikh0 个研究点目标入组 0 人开始时间: 待定最近更新: 2023年8月21日

研究概览

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•A total of 125 diabetic foot ulcer patients and 125 diabetic patients without foot ulcer (free from foot wounds and acute or chronic disease), admitted to surgery wards will be enrolled in the study. All wounds will be graded when they will get admitted to the hospital according to the Wagner classification system into five grades (grade I - grade V), the number of patients in each group will be 25.Foot ulcer was defined as a full-thickness skin defect that required >=14 days for healing. Cases and controls will be matched for age (Â±3 years), sex and duration of Diabetes.

•Patients with inflammatory or infectious diseases, autoimmune
•and rheumatic diseases, cancer, hematological diseases, malignancy, Pregnancy ,lactation ,Chronic inflammatory disorders, severe renal or liver failure, recent venous thromboembolism ,as well as those who were under treatment with immunodeficiency drugs , will be excluded from study . Foot ulcers caused by other conditions such as arterial insufficiency, venous insufficiency, or trauma will be excluded

发起方

Dr Shaheen B Shaikh