Efficacy of Insulin Like Growth Factor-1(IGF-1) on Bone Regeneration in Intrabony Defects : A Clinico-radiograph Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Bone Regeneration
研究概览
简要总结
The aim of this study is to clinically evaluate the efficacy of Insulin like Growth Factor (IGF-1) on bone regeneration in intrabony defects.
详细描述
In test group, after reflection of flap and degranulation, IGF-1 gel with hydroxyapatite will be placed in the defect and sutures will be placed.
In control group, after reflection of flap and degranulation, hydroxyapatite will be placed in the defect and sutures will be placed.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Systemically healthy male and female patients of age >18 years Intrabony defects - two wall or three wall defects Probing pocket depths (PPD) of >5mm.
排除标准
- •Medically compromised patients Pregnant women Heavy smokers Patients who underwent radiotherapy or chemotherapy are excluded
结局指标
主要结局
Bone Regeneration
时间窗: 3 months and 6 months
Radiovisiography (RVG) will be used to assess bone regeneration achieved post operatively after 3 months and 6 months.
clinical attachment level
时间窗: 3 months and 6 months
Assessment of clinical attachment level using UNC-15 probe at baseline and post operatively at 3 and 6 months.
Probig depth
时间窗: 3 months and 6 months
Assessment of probing depth using UNC-15 probe at baseline and postoperatively at 3 and 6 months.
次要结局
- Plaque Index(3 months and 6 months)
研究者
Dr R Viswa Chandra
PROFFESSOR AND HEAD OF THE DEPARTMENT
SVS Institute of Dental Sciences