Effects of the Low-level Laser Therapy (LLLT) on Muscle Strength (MS) of the Patients With Kidneys Failure (KF)

Not Applicable

Completed

• Conditions: Chronic Kidney Failure
• Interventions: Device: 4J LLLT; Device: 0J LLLT; Device: 6J LLLT; Device: 8J LLLT

• Registration Number: NCT02586376
• Lead Sponsor: Federal University of Health Science of Porto Alegre

Brief Summary

The low-level laser therapy (LLLT) has been used in many inflammatory disorders. More recently the LLLT was associated with an improvement in the muscle strength and endurance. But, these effects were described only in health or athletic individuals. In this randomized and controlled clinical trails, the investigators will study the effects of LLLT on muscle strength of the patients with kidneys failure on long time hemodialysis treatment. Additionally, investigators will explore three different intensities up the muscle strength.

Detailed Description

This study will be conducing in a large hospital that is reference in kidneys disorders treatments. 16 patients will be randomized for placebo, 4J, 6J, or 8J low-level laser therapy (LLLT). The maximal voluntary contraction (MVC) will be test by handgrip test before and after de LLLT. One-week interval between the LLLT will gave to reduce the influence between the treatments. Moreover the endurance test will be use to evaluate the muscle oxidation impact of the LLLT.

Study Timeline

• Study Start: 2015-10
• Study First Submitted: 2015-10-05
• Study First Submitted QC: 2015-10-22
• Study First Posted: 2015-10-26
• Primary Completion: 2016-01
• Status Verified: 2016-02
• Study Completion: 2016-02
• Last Update Submitted: 2016-02-02
• Last Update Posted: 2016-02-03

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 16

Inclusion Criteria

• chronic kidney failure,
• long time hemodialysis treatment (>18 months)

Exclusion Criteria

• any health disturbance that can reduces the handgrip test performance beyond to the produced by the chronic kidney failure.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
4J LLLT	4J LLLT	The Laser radiation will be made with 4J by spot.
0J LLLT	0J LLLT	The intervention will be made with the machine off.
6J LLLT	6J LLLT	The Laser radiation will be made with 6J by spot.
8J LLLT	8J LLLT	The Laser radiation will be made with 8J by spot.

Primary Outcome Measures

Name	Time	Method
Muscle Strength (Handgrip Test)	once a week throughout 4 weeks

Trial Locations

Locations (1)

Fabrício Edler Macagnan; 🇧🇷 Porto Alegre, RS, Brazil