ISRCTN89527210进行中（未招募）未知
A prospective randomised comparison of the effects of fluid restriction versus 0.9% saline infusion on plasma sodium and blood pressure in patients with pneumonia complicated by SIAD (syndrome of inappropriate antidiuresis)
Beaumont Hospital0 个研究点目标入组 40 人开始时间: 2018年1月29日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Age > 18 years
- •2. Eu-volemic
- •3. New asymptomatic hyponatraemia with plasma sodium 120 - 130 mmol/L
- •4. Biochemical confirmation of SIAD, including exclusion of adrenal insufficiency and hypothyroidism.
- •5. Radiographic confirmation of pneumonia
- •6. Clinical confirmation of pneumonia
- •7. Systolic blood pressure > 100 mmHg
排除标准
- •1. Symptomatic or severe hyponatraemia (plasma sodium < 120 mmol/L)
- •2. Volume depletion / hypovolaemia / systolic BP < 100 mmHg
- •4. Uncontrolled hyperglycemia
- •6. Diuretic therapy
- •7. Clinical imperative for intravenous fluids
- •8. Chronic hyponatraemia
研究者
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