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Comparison of different dialysis modality (conventional hemodialysis and on-line hemodiafiltration) on coronary and lower limbs' arterial calcification. ~Multicenter interventional study.

Not Applicable
Conditions
chronic renal failure
Registration Number
JPRN-UMIN000024241
Lead Sponsor
Shonan Kamakura General Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
100
Inclusion Criteria

Not provided

Exclusion Criteria

1)in hospital treatment within prior 12 weeks 2)have some infection or fever 3)atrial fibrillation 4)stent implanted in coornary artery or lower Limbs' artery 5)planned major amputation of lower limbs 6)severe cardiac failure with EF < 25% 7)warfarin user 8)involuntary movement of lower limbs 9)could not hold breath 10) pregnancy

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Coronary artery calcification score and lower limbs&#39; arterial calcification at study entry, 26 weeks, and 52 weeks, and compare them between hemodialysis and online hemodiafiltration.
Secondary Outcome Measures
NameTimeMethod
change of serum phosphate, calcium, intact parathyroid hormone, C reactive protein, albumin, beta2 microglobulin, ankle brachial pressure index, toe brachial pressure index, skin perfusion pressure, cardiac ultrasonography in hemodialysis and online hemodiafiltration.
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