NCT01513603Unknown2 期
Phase II Trial of CLAG-M in Relapsed ALL
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- Complete remission percentage
研究概览
简要总结
CLAG-M is an active, well tolerated regimen in acute myelogenous leukemia. Each of the agents is active in Acute Lymphoblastic Leukemia (ALL) as well. The current trial will determine the efficacy of the regimen in patients with relapsed ALL.
详细描述
Patients will receive standard dose CLAG-M (cladribine, cytarabine, mitoxantrone, filgrastim). Standard support care will be given. Efficacy will be assessed through bone marrow examinations and blood tests.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Relapsed or refractory acute lymphoblastic leukemia,
- •Burkitts leukemia/lymphoma,
- •Lymphoid blastic CML,
- •Lymphoblastic lymphoma.
排除标准
- 未提供
研究组 & 干预措施
CLAG-M
Experimental
干预措施: CLAG-M (Drug)
结局指标
主要结局
Complete remission percentage
时间窗: 1 month
次要结局
- Survival(2 years)
研究者
Karen Seiter
Professor of Medicine
New York Medical College
研究点 (1)
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