Multi-center prospective registry for patients with infective endocarditis and the need for cardiac surgery(Clinical, Multicenter Project of Analysis of Infective Endocarditis in Germany (CAMPAIGN))

• Conditions: I33.0; I33.9; Acute and subacute infective endocarditis; Acute endocarditis, unspecified

• Registration Number: DRKS00020815
• Lead Sponsor: niversitätsklinikum Köln

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-07-08
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 3000

Inclusion Criteria

patients with infective endocardtitis according to the Duke-criteria and indication for cardiac surgery
- informed consent
- age = 18 years

Exclusion Criteria

- lack of informed consent
- age < 18 years

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Major adverse cardiac and cerebrovascular events (MACCE) within 30 days after cardiac surgery<br><br>Composite endpoint consisting of:<br>- all-cause mortality<br>- non-fatal myocardial infarction<br>- non-fatal cerebrovascular event (stroke or TIA)

Secondary Outcome Measures

Name	Time	Method
- postoperative acute kidney injury<br>- perioperative myocardial infarction<br>- cerebrovascular event<br>- length of stay on intensive care unit<br>- length of stay in hospital<br><br>- all-cause mortality at 12 months<br>- long-term complications:<br> - re-hospitalization<br> - recurrence/reinfection of infective endocarditis