Non-contrast Abbreviated MRI for Secondary Surveillance of HCC
Completed
- Conditions
- Hepatocellular Carcinoma
- Registration Number
- NCT05690451
- Lead Sponsor
- Seoul National University Hospital
- Brief Summary
This prospective multicenter study aimed to compare the diagnostic performance of non-contrast abbreviated MRI in detecting recurrent HCC after curative treatment to that of contrast-enhanced liver CT.
- Detailed Description
This study was designed as a prospective single-arm intra-individual comparison multicenter study
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 210
Inclusion Criteria
- Age between 20-year old and 85-year old
- Patients with a history of curative treatment for HCC including surgical resection or local ablation
- No recurrence after curative treatment of HCC for more than two years
- Patient who has the plan to perform contrast-enhanced liver CT for secondary surveillance for HCC (i.e., to detect de novo or recurrent HCC)
Exclusion Criteria
- Estimated GFR less than 60
- Previous history of severe allergic reaction to the iodinated contrast agent
- Patients with claustrophobia who can't undergo MR examination
- Patients having cochlear implants or cardiac pacemaker
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Accuracy per patient Within 6 months from the study completion Accuracy for detection of recurrent HCC per patient
- Secondary Outcome Measures
Name Time Method Specificity per patient Within 6 months from the study completion Specificity for detection of recurrent HCC per patient
Sensitivity per patient Within 6 months from the study completion Sensitivity for detection of recurrent HCC per patient
Trial Locations
- Locations (3)
Seoul National University Bundang Hospital
🇰🇷Seongnam, Korea (the Republic Of), Korea, Republic of
Asan Medical Center
🇰🇷Seoul, Korea (the Republic Of), Korea, Republic of
Seoul National University Hospital
🇰🇷Seoul, Korea, Republic of