MedPath

Integration of HIV Care and Treatment Into Antenatal Care in Migori District, Kenya

Not Applicable
Completed
Conditions
HIV Infections
Interventions
Procedure: Integrated ANC, PMTCT, HIV services
Registration Number
NCT00931216
Lead Sponsor
University of California, San Francisco
Brief Summary

This study seeks to determine the most effective way to reach and provide pregnant women with accessible, comprehensive, and high quality HIV care and treatment.

Detailed Description

This study uses a prospective cluster randomized design. Twelve clinics similar in size, population, and services in Migori district, Kenya that provide ANC have been randomly assigned to receive "integrated ANC, PMTCT \& HIV services" (intervention arm) or "non-integrated services" (control arm). At the intervention clinics, pregnant women will receive ANC, PMTCT and HIV care and treatment (including HAART if required) at the same clinic visit from the ANC provider. At the control clinics, women will receive antenatal care and PMTCT services with referral to the HIV care and treatment department located in the same facility. The control sites more closely resemble the current approach followed for care and treatment of HIV-infected pregnant women in Kenya. The content of ANC, PMTCT, and HIV care will be the same in the two study arms and will follow current Kenyan national guidelines. The only difference between the two arms will be the provider/location of HIV care and treatment.

Outcomes will be compared for HIV-positive pregnant women who attend intervention versus control facilities. In addition we will conduct qualitative research with health care providers at the study health facilities in order to learn provider perspectives on the two service models and to explore the effects of integration on provider job satisfaction (including work load).

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1172
Inclusion Criteria
  • FOR SITE INCLUSION:

    • Each site must provide ANC services
    • Each site must provide HIV testing services for pregnant women
    • Each site must have an average of at least 20 new ANC clients per month
  • FOR ENROLLMENT OF HIV-POSITIVE WOMEN:

    • All women testing HIV-positive at one of the 12 ANC clinics included in the study will be asked to participate in the study
  • FOR HEALTH PROVIDER INCLUSION IN INTERVIEWS:

    • Health care staff must work within the ANC clinic at selected facilities
    • Staff must be able to read and speak English well enough to complete the informed consent process, participate in a one-on-one in-depth interview in English and complete a brief self-administered questionnaire
Read More
Exclusion Criteria
  • FOR SITE EXCLUSION:

    • If all of inclusion criteria are not met the site will be excluded
    • If site is already providing integrated ANC/HIV care services
  • FOR HEALTH PROVIDER INCLUSION IN INTERVIEWS:

    • If all of inclusion criteria are not met the site will be excluded
Read More

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Integrated ANC, PMTCT and HIV ServicesIntegrated ANC, PMTCT, HIV servicesHIV care and treatment services are integrated into antenatal care (ANC) services for women testing positive within the ANC at this facility.
Primary Outcome Measures
NameTimeMethod
Vertical transmission of HIV3 months postpartum
Secondary Outcome Measures
NameTimeMethod
Maternal HIV treatment outcomes6 months, 1 year
Provider job satisfaction1 year
Infant HIV testing uptake3 months postpartum
Patient enrollment, retention and adherence in HIV care and treatment6 months, 1 year

Trial Locations

Locations (1)

Migori District Hospital

🇰🇪

Migori, Kenya

© Copyright 2025. All Rights Reserved by MedPath