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Effect of phenylephrine drug on blood loss after cesarean sectio

Phase 4
Completed
Conditions
Health Condition 1: O60-O77- Complications of labor and delivery
Registration Number
CTRI/2021/08/035713
Lead Sponsor
Jawaharlal Institute of Postgraduate Medical Education and Research
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
106
Inclusion Criteria

Women more than 18 years of age undergoing elective or emergency cesarean delivery under spinal anesthesia

Exclusion Criteria

1.Preeclampsia, pregnancy-induced hypertension

2.Patient with heart disease

3.Any grade of placenta previa and placenta abruption

4.Patient with liver dysfunction, coagulopathy

5.Patients undergoing elective or emergency cesarean delivery under general anesthesia

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
To assess the effect of phenylephrine infusion on post-partum blood loss in patients undergoing cesar-ean delivery under spinal anaesthesiaTimepoint: post-partum blood loss will be assessed after the skin closure(end op)
Secondary Outcome Measures
NameTimeMethod
To assess the effect of phenylephrine infusion in the incidence of intra operative hypotension in patients undergoing cesarean delivery under spinal anaesthesiaTimepoint: intra operative hypotension will be recorded during the operation;To assess the effect of phenylephrine on a composite of neonatal outcome, APGAR score, Neonatal intensive care unit(NICU) admission and umbilical arterial pH.Timepoint: APGAR score, Neonatal intensive care unit(NICU) admission and umbilical arterial pH will be assessed after the skin closure(end op);To assess the effect of phenylephrine on intra op-erative maternal satisfaction in patients undergoing cesarean delivery under spinal anaesthesiaTimepoint: intra op-erative maternal satisfaction is assessed within 6 hours after the surgery ends
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