The maternal cardiovascular effect of phenylephrine-ephedrine compared to ephedrine protocols for cesarean section under spinal anesthesia: a multicenter randomized controlled trial
Phase 3
Recruiting
- Conditions
- Hypotension during spinal anesthesia for cesarean secttion
- Registration Number
- TCTR20191210002
- Lead Sponsor
- one
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Female
- Target Recruitment
- 316
Inclusion Criteria
18 years of age and older
scheduled for elective cesarean section in official time
37-42 weeks gestational age
ASA physical status I-II
normal singleton
Exclusion Criteria
multiple gestation
complicated pregnancy eg. placenta previa, abruptio placenta
preexisting cardiovascular disease, renal and liver impairment, thyroid dysfunction, increased intraocular pressure
ongoing infection
history of drug abuse, MAOI or TCA group 1 month prior to delivery, vasopressor agent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method average maternal heart rate after spinal anesthesia until operation end beat per minute
- Secondary Outcome Measures
Name Time Method average maternal systolic blood pressure after spinal anesthesia until operation end mmHg,severity of nausea and vomiting after spinal anesthesia until operation end score,satisfaction after spinal anesthesia before delivery VAS,total dose of vasopressor after spinal anesthesia until operation end mg, mcg,atropine used after spinal anesthesia until umbilical cord clamping mg,arrhythmia after spinal anesthesia until operation end occurance,Apgar score 1st,5th minutes post-delivery score