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Impact of Clopidogrel on diameter and wall thickness of coronary arteries after heart transplantatio

Conditions
Transplant vasculopathy after heart transplantation characterized by Stanford type B2 lesions in coronary angiography and by microvasculopathy proven in biopsy.
Therapeutic area: Diseases [C] - Cardiovascular Diseases [C14]
Registration Number
EUCTR2009-016914-25-DE
Lead Sponsor
Deutsches Herzzentrum Berlin
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Recruiting
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Age: > 18
Gender: men and women
In women: During the pharmacological treatment a recognized method of contraception must be used.
Written consent to participate in the clinical study, including consent to data protection regulations.
Heart transplantation >= 2,5 years before.
Taking of Everolimus as basic immunosuppression for at least 4 weeks and for a maximum of 6 months in addition.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 200
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 10

Exclusion Criteria

Known over-sensitivy to Clopidogrel or another constituent of the preparation.
Age < 18 years
Pregnant or breast feeding women
Heart transplantation < 2 years ago
Acute bleeding

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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