Estimation of antibodies in saliva and blood against coronavirus after COVID-19 vaccinatio
- Registration Number
- CTRI/2022/04/041945
- Lead Sponsor
- Manipal Centre for Infectious diseases Manipal Seed Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 0
Human participants (healthy volunteers or patients coming to Manipal College of Dental Sciences, Manipal or Kasturba Medical college /Hospitals, who have received the two doses of COVID19 vaccination (Covaxin or Covishield) and volunteer to participate after oral and written informed consent will be included
Participants should be between the ages of 18-60 years
Participants who are not vaccinated will be excluded
Participants who have received the 2nd dose of Covishield or Covaxin 2 week before will be excluded.
Participants presenting with any immunocompromised condition, genetic abnormalities related to IgA, pregnant and lactating females; patients undergoing any chemotherapy, radiation therapy; Patients on corticosteroids, antiviral therapy, immunomodulators will be excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mean serum and salivary IgA levels.Timepoint: Baseline
- Secondary Outcome Measures
Name Time Method Age, gender, smoking status, oral hygiene status as calculated by patients Oral Hygiene index-simplified, DMF, presence of any other systemic diseases, and comorbidities.Timepoint: baseline