To study antibodies in saliva and blood of patients of rheumatoid arthritis

Not Applicable

Completed

• Conditions: Health Condition 1: M05- Rheumatoid arthritis with rheumatoid factor

• Registration Number: CTRI/2018/11/016447
• Lead Sponsor: Maulana Azad Medical College

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2019-03-15
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 111

Inclusion Criteria

All adult patients with Rheumatoid Arthritis (RA), as defined by the 2010 ACR/EULAR classification criteria, will be eligible for the study. Healthy volunteers among the hospital staff will also be recruited to define normal salivary IgA Anti-CCP levels in healthy population. They will include volunteers with good orodental hygiene.

Exclusion Criteria

Exclusion criteria for Healthy Volunteers:

No first degree relatives with RA, no tobacco use and no past history of connective tissue disorders.

Exclusion criteria for RA patients:

Subjects with a history of smoking/current smokers/oral tobacco use

,with poor orodental hygiene,RA patients with coexisting connective tissue disorders like psoriatic arthritis ,Systemic Lupus Erythematosus (SLE),Primary Sjögrenâ??s Syndrome,with a history of pulmonary tuberculosis

Study & Design

• Study Type: Observational
• Study Design: Not specified