跳至主要内容
临床试验/NCT03299998
NCT03299998已完成不适用

Evaluation of Maxillary and Mandibulary Nerve Blocks on Morphine Consumption in Double-jaw Surgery, a Retrospective Study

Hospices Civils de Lyon1 个研究点 分布在 1 个国家目标入组 92 人开始时间: 2017年7月25日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
92
试验地点
1
主要终点
Cumulative morphine consumption within 24 hours post-surgery

研究概览

简要总结

Background and Objectives: Double-jaw surgery is one of the most painful oral surgery, requiring multimodal analgesia including controlled morphine pump and its secondary effects. The aim of this study was to evaluate the effectiveness of face block (mandibulary and maxillary block analgesia) on the first 24 hours on morphine consumption in patients admitted for double jaw surgery.

详细描述

Methods: Patients undergoing double-jaw surgery between January 2015 and May 2017 were enrolled. Patients were separated into 2 groups: patients receiving maxillary-mandibulary nerve block and those no receiving it. The primary endpoint was the morphine consumption within 24 hours post-surgery. Secondary endpoints were the intra-operative remifentanil consumption, incidence of postoperative nausea and vomiting at 24 hours, morphine consumption in recovery room, length of stay in hospital.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

接受健康志愿者

入选标准

  • Male and female who underwent double jaw surgery

排除标准

  • opposition to the study
  • an additional surgical procedure
  • preoperative consumption of morphine or derived from morphine
  • perioperative N20

结局指标

主要结局

Cumulative morphine consumption within 24 hours post-surgery

时间窗: 24 hours

Cumulative morphine consumption measured using patient controlled analgesia (PCA-pump).

次要结局

  • Peroperative remifentanil consumption(End of surgery (2 hours in average))
  • Cumulative morphine consumption within 12 hours post-surgery(12 hours)
  • Hospital length of stay(Up to hospital discharge (5 days in average))
  • Cumulative morphine consumption within 48 hours post-surgery(48 hours)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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