Study on analgesic effectiveness of ultrasound guided transverse abdominis plane block using different volumes and concentrations of levobupivacaine in laparoscopic cholecystectomy
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 110
- 试验地点
- 1
- 主要终点
- 1.To compare the duration of postoperative analgesia obtained in the two study groups.
研究概览
简要总结
A comparative study on analgesic effectiveness of two different volumes and concentrations of levobupivacaine for ultrasound-guided Transverse Abdominis Plane block to be conducted on patients undergoing laparoscopic cholecystectomy.The patients will be given General anaesthesia followed by Transverse Abdominis Plane block with 20ml of local anaesthetic (10ml 0.5% levobupivacaine and 10ml sterile water) in Group A and 30 ml of local anaesthetic (10ml 0.5% levobupivacaine and 20 ml sterile water)in Group B. Both Groups will be compared intraoperatively for analgesia using hemodynamic parameters and use of fentanyl and will be compared postoperatively by checking VAS score at 20min,12h and 24h, first time of requirement of analgesic and total analgesic used.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients belonging to ASA Grade I to ASA Grade II.
- •2.Patients scheduled for elective laparoscopic cholecystectomy under General Anaesthesia with endotracheal intubation.
排除标准
- •1.Patients not willing to give consent to the above study.
- •2.Patients with cardiac, endocrinological or neurological disease 3.Patients with coagulation disorders 4.Patients with a history of known allergy to study drugs.
- •5.Lap cholecystectomies converted to open cholecystectomies.
结局指标
主要结局
1.To compare the duration of postoperative analgesia obtained in the two study groups.
时间窗: minutes to hours
次要结局
- 1. To compare the pain score in the two study groups(2. To study haemodynamic changes after transverse abdominis plane infiltration of Levobupivacaine in the two study groups.)
研究者
Dr Sumedha Dhar
Bankura Sammilani Medical College and Hospital