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Clinical Trials/CTRI/2025/07/090748
CTRI/2025/07/090748
Not yet recruiting
Phase 3

A Randomized double-blind study to compare the analgesic efficacy of Ultrasound guided supra-inguinal versus conventional infra-inguinal approach for fascia iliaca compartment block in patient with hip bone fracture

Department of Anaesthesiology1 site in 1 country60 target enrollmentStarted: July 30, 2025Last updated:

Overview

Phase
Phase 3
Status
Not yet recruiting
Sponsor
Department of Anaesthesiology
Enrollment
60
Locations
1
Primary Endpoint
To compare the duration of pain relief between supra-inguinal fascia iliaca compartment block (SIFIB) versus infra-inguinal fascia iliaca compartment block (IIFIB) in patient with unilateral hip bone fracture in terms of first dose of rescue analgesic.

Overview

Brief Summary

Title: A Randomized Double-Blind Study to Compare the Analgesic Efficacy of Ultrasound-Guided Supra-Inguinal versus Conventional Infra-Inguinal Approach for Fascia Iliaca Compartment Block in Patients with Hip Bone Fracture

Summary: This prospective, randomized, double-blind clinical study, conducted at JNMC, AMU, aims to compare the analgesic effectiveness of ultrasound-guided supra-inguinal (SIFIB)versus infra-inguinal fascia iliaca compartment block (IIFIB) in patients with unilateral hip bone fractures. Hip fractures are common in the elderly and associated with severe pain and complications. The study includes 60 patients, randomly assigned to either SIFIB or IIFIB groups (30 each), to assess pain relief efficacy.

The primary objective is to compare the duration of analgesia based on the time to first rescue analgesic dose. Secondary objectives include evaluating pain scores using the Numerical Rating Scale (NRS), total analgesic consumption over 24 hours, and recording any adverse effects or complications.

This trial emphasizes the importance of early and effective regional analgesia as a safer alternative to opioids and NSAIDs, especially in elderly patients with comorbidities.

Study Design

Study Type
Interventional
Allocation
Randomized
Masking
Double

Eligibility Criteria

Ages
18.00 Year(s) to 75.00 Year(s) (—)
Sex
All

Inclusion Criteria

  • Patient willingness to participate in the study.
  • Patient between 18 to 75 years of age.
  • A radiographically confirmed unilateral hip bone fracture with NRS score more than
  • BMI between 18-30 kilogram per meter square
  • ASA Grade I and II.

Exclusion Criteria

  • Having suffered from major trauma or fracture of other bone 2)Refusal to participate.
  • Manifesting coagulopathy or deranged INR.
  • Currently on chronic analgesics, 5)A history of allergy to local anesthetics, 6)An infection in the area where FICB was to be performed, 7)Having significant visual, hearing or cognitive impairment 8)History of alcohol or drug abuse 9)Neuro-vascular disorder in the affected leg.

Outcomes

Primary Outcomes

To compare the duration of pain relief between supra-inguinal fascia iliaca compartment block (SIFIB) versus infra-inguinal fascia iliaca compartment block (IIFIB) in patient with unilateral hip bone fracture in terms of first dose of rescue analgesic.

Time Frame: The intensity of pain will be recorded in both groups at the following time points: before the procedure (T0) and at 1hr (T1), 3hr (T2), 12hr (T3), and 24 hr (T4) after the procedure

Secondary Outcomes

  • To compare the degree of pain relief in terms of Numerical Rating Scale(NRS).(•To record analgesic consumption during first 24 hours.)

Investigators

Sponsor
Department of Anaesthesiology
Sponsor Class
Government medical college
Responsible Party
Principal Investigator
Principal Investigator

Dr Khursheed Jamal

Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh

Study Sites (1)

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