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Clinical Trials/NCT06206863
NCT06206863
Recruiting
N/A

Community-Based Physical Activity Across the Cancer Continuum

Roswell Park Cancer Institute1 site in 1 country200 target enrollmentAugust 20, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Hematopoietic and Lymphoid System Neoplasm
Sponsor
Roswell Park Cancer Institute
Enrollment
200
Locations
1
Primary Endpoint
Proportion of patients referred to the intervention (Feasibility)
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

This clinical trial evaluates a community-based physical activity program for underserved cancer survivors. Cancer and its treatment significantly influence physical, psychosocial, and cognitive functioning. Historically, community sites (local and national) have not been staffed to offer support services such as physical, and occupational therapies (everyday life activities to promote health and well-being) or nutrition counselling, and do not offer a whole-person model of care. In this study, researchers have partnered with the YMCA to provide tailored home-based exercise programs for underserved cancer patients and survivors. Accessing exercise professionals may allow patients to prevent acute problems from becoming chronic, long-lasting physically weak impairments that directly influence patients' quality of life.

Detailed Description

PRIMARY OBJECTIVE: I. To assess the feasibility and acceptability of a community-based 12-week physical activity intervention. SECONDARY OBJECTIVE: I. To assess the effectiveness of a virtual physical activity intervention by evaluating pre-post changes in quality of life (QoL). EXPLORATORY OBJECTIVE (OPTIONAL): I. To virtually assess changes in functional performance in a small subgroup. OUTLINE: Participants participate in virtual exercise classes at least three times a week (TIW) over 20-60 minutes for 12 weeks. Participants are expected to work towards achieving the national physical activity exercise guidelines of 150 minutes of moderate intensity aerobic based physical activity and 2-3 strength training sessions each week. After completion of study intervention, patients are followed up at 1 week.

Registry
clinicaltrials.gov
Start Date
August 20, 2024
End Date
December 30, 2027
Last Updated
4 months ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Have had a previous cancer diagnosis OR are a caregiver for a patient who has had a previous cancer diagnosis
  • Not in active treatment for cancer
  • Over 18 years of age

Exclusion Criteria

  • Have uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, atrial fibrillation (AFIB), multiple myeloma, or psychiatric illness/social situations that would limit compliance with study requirements
  • Have orthopedic or neuromuscular disorders or arthritis that preclude participation in exercise
  • Are pregnant or nursing
  • Are unwilling or unable to follow protocol requirements
  • Have any condition which in the investigator's opinion deems the subject an unsuitable candidate to participate in this study

Outcomes

Primary Outcomes

Proportion of patients referred to the intervention (Feasibility)

Time Frame: Up to 12 weeks

At the provider level, feasibility will be defined as the proportion of patients that were referred to the intervention versus (vs.) the proportion of patients that enrolled in the study. Will estimate the referral rates with 95% confidence intervals obtained from generalized estimating equation (GEE) logistic regression models, accounting for the within provider clustering.

Proportion of patients that enrolled in the study (Feasibility)

Time Frame: Up to 12 weeks

At the provider level, feasibility will be defined as the proportion of patients that were referred to the intervention vs. the proportion of patients that enrolled in the study.

Retention rate (Feasibility)

Time Frame: At the end of the 12-week intervention

At the patient level, feasibility will be defined as the proportion of patients still on study. Will estimate with 95% confidence intervals obtained from GEE logistic regression models, accounting for the within provider clustering.

Adherence rate (Acceptability)

Time Frame: At post 12-weeks

Adherence will be defined as the percentage of patients on study after 12-weeks who complete at least 70% of the intervention videos. Will estimate with 95% confidence intervals obtained from GEE logistic regression models, accounting for the within provider clustering.

Patient satisfaction (Acceptability)

Time Frame: Up to 12 weeks

Acceptability will be determined by measuring adherence to the intervention and by measuring patient satisfaction. Patient satisfaction will be determined through pre-post intervention surveys. Will use the appropriate generalized linear model (ex. linear or logistic), as determined by the question type and accounting for the within provider clustering.

Secondary Outcomes

  • Overall quality of life(Up to 12 weeks)

Study Sites (1)

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