Efficacy of rTMS upper limb paralysis after cervical SCI
- Conditions
- Cervical spinal cord injury
- Registration Number
- JPRN-jRCTs032220059
- Lead Sponsor
- Kikuchi Naoshisa
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 32
(1) Age: 20-80
(2) Under the agreement with written consent form
(3) Diagnosed as cervical spinal cord injury by a physician
(4) Inpatient at Chiba Rehabilitation Center
(5) AIS C or D
(6) 3 months after onset
(7) The weekly upper extremity motor score ( the Prehension Performance item of GRASSP; The Graded Redefined Assessment of Strength, Sensibility and Prehension) is limited to a change within the standard error for two consecutive weeks
(1) Fit into following cases
History of harmful sides effects due to magnetic or electrical stimulation, History of seizure or epilepsy, History of disease or injury of head, brain, peripheral nerves including brain surgery, Medical device implantation such as cardiac pacemaker, neurosurgical clips, battery or pumps, non-titanium metal implants in the head or the stimulus target area of trunk, Chronic severe migraine, Pregnant or suspicion of pregnancy
(2) Unable to confirm that the implant is titanium
(3) Inappropriate patient decided by a physician
(4) Current participation in clinical trials for unapproved drug or clinical device
(5) History of botulinum toxin therapy within 4 months
(6) Over 17 points the Prehension Performance item of GRASSP (The Graded Redefined Assessment of Strength, Sensibility and Prehension)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Changes in measured value prime points for pre- and post-intervention measurements of the Graded Redefined Assessment of Strength, Sensibility and Prehension Version 2 (GRASPP); Prehension Performance item
- Secondary Outcome Measures
Name Time Method GRASPP's Preintervention Performance item changes in measured value prime points from pre-intervention and post-intervention measurements at 1 month after the intervention, Total score of GRASSP, Subtest scores other than Prehension Performance item of GRASSP, American spinal injury association upper extremity motor score, Spinal Cord Independence Measure, Magnetic resonance imaging, Motor evoked potential elicited by transcranial magnetic stimulation, Safety Assessment