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Comparative evaluation of Amniotic membrane/Collagen membrane for the management of periodontal intra-bony defects

Not Applicable
Conditions
Health Condition 1: K053- Chronic periodontitis
Registration Number
CTRI/2020/03/024075
Lead Sponsor
nivedhav
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
20
Inclusion Criteria

1 Age 21-50 years

2 Patients with moderate to severe localized periodontitis with a Probing Depth (PD) >=6 mm and an intrabony component of more than 3 mm as detected on Intra oral periapical radiographs (IOPAR) and bone sounding (Sali 2016).

3 Intrabony defect angle of less than 40 degree (Sali 2016).

4 Circumferential defect with interdental intrabony defect depth of more than 3mm will be included.

5 Nonsmoker (Never smoker) or former smoker (Does not smoke now and has not smoked at all for a minimum of the last 12 consecutive months)

Exclusion Criteria

1 Current Smokers (smokers who have smoked more than 100 cigarettes in their lifetime and currently smoke)

2 Systemic chronic conditions known to be associated with periodontitis or with changes in systemic inflammation: Diabetes, Cardiovascular diseases, Rheumatoid Arthritis, Rheumatic Fever, SLE, Malignancy, Respiratory diseases, Renal diseases, Other (e.g., autoimmune diseases, fungal infections, immunological deficiencies, etc.)

3 Pregnant / Lactating mothers

4 Previous History of periodontal treatment at the selected site

5 Teeth with intrabony defect component and furcation involvement were also excluded from the study.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Change in Probing Pocket Depth or Clinical Attachment Level and Radiographic bone gainTimepoint: baseline, 1 month, 3 month and 6 month
Secondary Outcome Measures
NameTimeMethod
Wound Healing index, Visual Analogue ScaleTimepoint: at 3, 10 days
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