HPV FOCAL study: human papillomavirus testing for cervical cancer screening

Not Applicable

Completed

• Conditions: Human papillomavirus (HPV), cervical cancer; Cancer; Cervical cancer

• Registration Number: ISRCTN79347302
• Lead Sponsor: Provincial Health Services Authority (Canada)

Brief Summary

2010 Results article in http://www.ncbi.nlm.nih.gov/pubmed/20334685 preliminary results 2015 Results article in http://www.ncbi.nlm.nih.gov/pubmed/26674353 results 2018 Results article in http://www.ncbi.nlm.nih.gov/pubmed/29971397 results 2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34620663/ (added 11/10/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-04-20
• Study Completion: 2014-12-31
• Last Update Posted: 26 October 2021

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 28000

Inclusion Criteria

Current information as of 04/11/2008:
1. Women aged 25 to 65 years
2. Registered with MSP
3. Attending a collaborating BC healthcare provider for regular cervical cancer screening (pap tests)

Initial information at time of registration:
1. Women aged 25 to 65 years
2. British Columbia residents
3. Eligible for routine cervical screening

Exclusion Criteria

Current information as of 01/12/2009 (effective 25/11/2009):
1. Pap smear less than one year ago
2. Pregnant (at time of initial sample)
3. History of moderate to severe cervical intraepithelial neoplasia (greater than CIN2) requiring treatment less than 5 years ago
4. History of invasive cervical cancer at any time
5. Complete hysterectomy with cervix removal
6. Human immunodeficiency virus (HIV) positive or receiving immunosuppressive treatments
7. Unable or unwilling to sign the Information and Consent form

Information as of 04/11/2008:
1. Pap smear less than one year ago
2. Pregnant
3. History of moderate to severe cervical intraepithelial neoplasia (greater than CIN2) requiring treatment less than 5 years ago
4. History of cervical cancer at any time
5. Complete hysterectomy with cervix removal
6. Human immunodeficiency virus (HIV) positive or receiving immunosuppressive treatments
7. Received HPV vaccination
8. Unable or unwilling to sign the Information and Consent form

Initial information at time of registration:
1. Pregnant
2. History of cervical cancer
3. Hysterectomy
4. Human immunodeficiency virus (HIV) positive
5. Unable to give informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified