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临床试验/NCT04824781
NCT04824781已完成不适用

Recovery From Paranoia: a Qualitative Exploration

University of Oxford1 个研究点 分布在 1 个国家目标入组 15 人开始时间: 2021年6月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
15
试验地点
1
主要终点
Qualitative interview accounts

研究概览

简要总结

Paranoia, the experience of undue or excessive mistrust, exists on a continuum which includes suspicious thoughts, ideas of reference, and persecutory delusions. Persecutory delusions refers to strong unfounded fears that others intend harm. These fears are very common. They affect around 70% of patients with schizophrenia. They can be distressing and make day-to-day tasks difficult. However, current treatments are limited and a significant proportion of people do not benefit sufficiently. Therefore, improvements in treatment are needed. A better understanding of the experience of recovery from paranoia will help inform theoretical understanding and treatment development. Currently we do not fully understand what causes paranoia to occur, persist, or end. As such, it is critical to understand the experiences of those who have recovered, in particular what elements encourage recovery. Therefore, the aim of this study is to gain a first-person perspective on how people recover from paranoia and what psychological processes are important for recovery from paranoia. Using a qualitative approach appropriate for exploratory research, semi-structured interviews will be conducted with 12-15 patients who have recovered from paranoia. Interviews will be analysed using interpretative phenomenological analysis, a qualitative research approach which aims to provide insight on how an individual, in a particular situation, makes sense of their experience.

研究设计

研究类型
Observational
观察模型
Other
时间视角
Retrospective

入排标准

年龄范围
16 Years 至 —(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Participant has recovered from the paranoia. This is defined as: A.) conviction in persecution beliefs is rated as less than 10% and B.) not experiencing significant distress related to paranoia and C.) currently scoring outside the clinical range of the revised Green et al., Paranoid Thoughts Scale (R-GPTS; Freeman, 2019);
  • Participants should have had experiences of paranoia in the context of non-affective psychosis. This will be determined by participant's agreement that they previously had the sort of thoughts listed in the revised Green et al. Paranoid Thoughts Scale (R-GPTS; Freeman, 2019);
  • Participant is currently a patient of Oxford Health NHS Foundation Trust;
  • Participant is willing and able to give informed consent for participation in the study;
  • Aged 16 years or above;
  • Participant has sufficient English language skills to participate in the interview.

排除标准

  • The following exclusion criteria will apply based on concerns regarding risk and capacity to consent:
  • Currently experiencing acute psychiatric symptoms which preclude ability to participate in a sustained interview;
  • Diagnosis of a moderate to severe intellectual disability;
  • High levels of associated risk to self or to others e.g. actively suicidal;
  • Primary diagnosis of alcohol or drug misuse; personality disorder; significant forensic history;
  • At the time of recruitment COVID-19 restrictions do not permit face-to-face interviews and the participant is not willing or able to conduct the interview remotely via video call.

结局指标

主要结局

Qualitative interview accounts

时间窗: March 2021-March 2022

Semi-structured interpretative phenomenological analysis (IPA) interviews will be used.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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