To compare & evaluate the efficacy of artificial bone particles with specialized blood clot in the treatment of severe gum disease

Phase 2

• Conditions: Health Condition 1: - Health Condition 2: M278- Other specified diseases of jawsHealth Condition 3: M858- Other specified disorders of bonedensity and structure

• Registration Number: CTRI/2023/11/059644
• Lead Sponsor: Dr Monika Patil

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

1)Patients in the age group between 30-60 yrs.

2)Patients diagnosed with Chronic Periodontitis.

3)Patients who are non-smokers or do not consume tobacco in any other form.

4)Patients are in good systemic health with no contraindication to periodontal surgery.

5) Patients having pocket depths >5mm, intraosseous defects > 3mm and with radiographic evidence of vertical / angular bone loss in the affected sites.

Exclusion Criteria

1) One-walled osseous defects.

2) Patients suffering from any systemic diseases or with a compromised immune system.

3) Patients who had received any type of periodontal therapy for the past 6 months.

4) Patients taking immunosuppressant drugs like corticosteroids.

5) Patients with a known history of allergy to Doxycycline or Chlorhexidine or any other medicine used in the study.

6) Patients showing unacceptable oral hygiene compliance during / after Phase I periodontal therapy.

7) Patients taking any drug known to cause gingival enlargement.

8) Pregnant and/or lactating mothers.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1.Plaque Index (P.I.) (Tureskey-Gilmore-Glickman Modification of Quigley Hein) <br/ ><br> <br/ ><br>2.Gingival Index (G.I.) (Loe & Silness, 1963) <br/ ><br> <br/ ><br>3.Probing Pocket Depth (PPD) <br/ ><br> <br/ ><br>4.Clinical Attachment Level (CAL) <br/ ><br>Timepoint: Baseline, 1 Month, 3 Months, 6 Months

Secondary Outcome Measures

Name	Time	Method
Measurement of bone fill from CEJ to the base of the defect using radiovisiography (RVG) with EzDenti imaging softwareTimepoint: Baseline, 1 Month, 3 Months, 6 Months