Effects of Maternal Obesity on Offspring Brain Development
Active, not recruiting
- Conditions
- Healthy
- Registration Number
- NCT03499587
- Lead Sponsor
- Arkansas Children's Hospital Research Institute
- Brief Summary
The goal of this study is to see if there are negative effects of maternal obesity during pregnancy on offspring's brain development.
- Detailed Description
This study will recruit pregnant women who are either obese or normal weight and otherwise healthy. We will measure their body composition, food intake and other characteristics during pregnancy. When their babies are born, we will evaluate the brain development of their babies using magnetic resonance imaging and electroencephalography at age two weeks. We will then compare the findings and see if their are differences.
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 13
Inclusion Criteria
- BMI 18.5-25 or >30 with early OB visit medical records accessible
- singleton pregnancy
- about 36wks of pregnancy
- at least 18 years of age
Exclusion Criteria
- hypertension, diabetes, or other preexisting medical conditions
- medications known to influence fetal growth
- recreational drugs, nicotine or tobacco use of alcohol use while pregnant
- pregnancy conception with assisted fertility treatment
- medical complications developed during pregnancy
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Determine whether maternal obesity correlates with abnormal brain development in newborns 2 weeks Brain will be imaged at 2wks using an MRI
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Arkansas Children's Nutrition Center
🇺🇸Little Rock, Arkansas, United States