iquid biopsies in patients with peritoneal metastases of colorectal cancer.
- Conditions
- peritoneal metastases (PM), colorectal cancer (CRC), cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), liquid biopsy, circulating tumor DNA (ctDNA)Dutch: peritoneale metastasen (PM), colorectaal carcinoom (CRC), cytoreductie en hypertherme intraperitoneale chemotherapie (HIPEC), liquid biopsy, circulerend tumor DNA (ctDNA)
- Registration Number
- NL-OMON22788
- Lead Sponsor
- VU medisch centrumAfdeling HeelkundeBoelelaan 11171081 HV, Amsterdam
- Brief Summary
After completion of the study and analysis of the data results will be made public without restriction, independent of the outcome. They will be submitted for publication to an international peer-reviewed journal. The principle investigators and study coordinators will prepare the manuscript together with those who substantially contributed to the study.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Orally and written informed consent
- Age 18 years and older
- Patients who are legally or mentally incapable or unable to give informed consent
- Patients younger than 18 years
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Plasma levels of ctDNA preoperatively.
- Secondary Outcome Measures
Name Time Method Plasma levels of ctDNA postoperatively.