Antimicrobial activity of Curcuma zedoaria Rosc white turmeric extract as denture cleansing agent An in vivo study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- microbial analysis of swabs collected from denture to show antimicrobial activity
研究概览
简要总结
Aim: To study the antimicrobial efficacy of C. zedoaria (whiteturmeric) extract as denture cleansing agent
Hypothesis: The hypothesis of this study is that C. zedoria extract is an effective alternative to commercially available synthetic denture decontaminants
Purpose: The purpose of this study is to evaluate and compare the disinfection of acrylic removable prosthesis by C. zedoria extract, with the conventional method of disinfection on contaminated prosthesis. The significance of the study is that curcumin is an economical, effective, non-toxic, acceptable and eco-friendly method of disinfection for contaminated prosthesis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 35.00 Year(s) 至 95.00 Year(s)（—）
- 性别
- All
入选标准
- •Completely edentulous subjects with maxillary and mandibular heat-cured acrylic dentures (6 months – 4 years of use) Subjects with satisfactory denture hygiene (no visible calculus on denture) Subjects who gave informed consent.
排除标准
- •Subjects with removable partial denture Subjects with cast partial denture.
- •Subjects with implant-supported denture.
- •Subjects with a less than 6 month of usage Subjects with cracks or repairs or relining in their dentures.
- •Subjects on antibiotic, steroid or anti-fungal therapy Subjects using mouthwashes and denture cleansers prior to study.
- •Subjects who did not give written informed consent.
- •Subjects with immunosuppressive disorders.
结局指标
主要结局
microbial analysis of swabs collected from denture to show antimicrobial activity
时间窗: baseline, 2 weeks
次要结局
未报告次要终点
研究者
Vidisha
JSS Dental College and Hoospital, JSS Academy of Higher Education