Retrospective study of elderly patients with classical Hodgkin lymphoma in Japan: HORIZON study
Not Applicable
- Conditions
- Classical Hodgkin lymphoma
- Registration Number
- JPRN-UMIN000033264
- Lead Sponsor
- HORIZON study investigators
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up continuing
- Sex
- All
- Target Recruitment
- 171
Inclusion Criteria
Not provided
Exclusion Criteria
1) Positive for HIV 2) Patients who received first-line treatment outside the study institution 3) Patients who were not treated or managed by the hematologists in each study institution (ex. Second opinion) 4) Patients who were diagnosed as having methotrexate-associated lymphoproliferative disorders.
Study & Design
- Study Type
- Others,meta-analysis etc
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 5-year overall survival rate
- Secondary Outcome Measures
Name Time Method 1) 5-year progression-free survival rate 2) 5-year event-free survival rate 3) Overall response rate and complete response rate of first-line therapy 4) The rate of bleomycin lung toxicity (BLT) 5) The rate of patients who completed 100%-dose ABVD therapy 6) The average relative dose-intensity of ABVD therapy 7) Charlson Comorbidity Index (CCI) score at the baseline 8) Investigation of pathological biomarkers