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Clinical Trials/NCT02779309
NCT02779309
Completed
Not Applicable

An Algorithm for Predicting Death Among Older Adults in the Home Care Setting: Study Protocol for the Risk Evaluation for Support: Predicting Elder Life in the Community Tool (RESPECT)

Ottawa Hospital Research Institute0 sites486,000 target enrollmentJanuary 2007
ConditionsDeath

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Death
Sponsor
Ottawa Hospital Research Institute
Enrollment
486000
Primary Endpoint
6-month Mortality
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

To develop a mortality risk prediction model that can be applied to the wide spectrum of risks that are seen in the home care setting.

Detailed Description

ABSTRACT Introduction: Older adults living in the community often have multiple, chronic conditions and functional impairments. A challenge for healthcare providers working in the community is the lack of a predictive tool that can be applied to the broad spectrum of mortality risks observed and may be used to inform care planning. Objective: To develop a mortality risk prediction model for older adults in the home care setting. The final algorithm will be implemented as a web-based calculator that can be used by older adults needing care, as well as their informal and formal caregivers. Design: Open cohort study using the Resident Assessment Instrument for Home Care (RAI-HC) data in Ontario, Canada, from January 1, 2007, to December 31, 2013. Participants: The derivation cohort will consist of approximately 437 000 home care recipients from January 1, 2007, to December 31, 2012. A split sample validation cohort will include approximately 122 000 recipients from January 1 to December 31, 2013. Main outcome measures: Predicted survival from the time of an RAI-HC assessment. All deaths (N ≈ 245 000) will be ascertained through linkage to the provincial vital statistics records. Statistical analysis: Proportional hazards regression will be estimated after assessment of assumptions. Predictors will include sociodemographic characteristics, social support, health conditions, functional status, cognition, symptoms of decline, and prior healthcare use. Model performance will be evaluated for 6- and 12-month predicted risks, including measures of calibration (e.g., calibration plots) and discrimination (e.g., c-statistics). The final algorithm will be generated by combining development and validation data.

Registry
clinicaltrials.gov
Start Date
January 2007
End Date
December 2017
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Have received a structured RAI-HC assessment
  • Between 50 and 105 years of age

Exclusion Criteria

  • Not eligible for Ontario's universal health insurance program (OHIP)
  • Did not receive a structured RAI-HC assessment

Outcomes

Primary Outcomes

6-month Mortality

Time Frame: 6 months

Mortality status at 6 months after receiving a structured Resident Assessment Instrument for Home Care (RAI-HC) Assessment.

Secondary Outcomes

  • 12-month Mortality(12 months)

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